I studied medicine at the National and Kapodistrian University of Athens, Greece, and graduated in 2006. In February 2017, I defended my doctoral thesis entitled "Systemic lupus erythematosus: biomarkers and biologics", which I carried out at the Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden. My thesis focused on novel biomarkers in lupus nephritis, and clinical and immunological effects of biological therapies in systemic lupus erythematosus, including effects on health-related quality of life.
With my research, I aim at improving the management and surveillance for people living with systemic lupus erythematosus and lupus nephritis. At the post-doctoral level, I have continued on the same trajectories as during my doctoral education, and focused on identification of biomarkers that reflect activity and portend flare, response to therapy (especially B cell targeted biologics), and long-term outcome.
Last but not least, I have an interest in medical pedagogy, and I am currently working on the development of a novel virtual patient modality for interprofessional learning.
In 2021, I joined Dr Parodis’s research team, not only because we share a passion for patients with systemic lupus erythematosus, but also for post-doctoral research in evaluating patient-reported outcomes in other rheumatic disorders.
The aim of my current project is to evaluate the ability of patient responses to screening questionnaires to predict definite diagnosis of spondyloarthritis.
I have been conducting research on rheumatoid arthritis and systemic lupus erythematosus since 2014. In 2020, I joined Dr Parodis’s research team to proceed with my doctoral education, which now is focused on optimisation of treatment outcomes in people living with systemic lupus erythematosus.
Within my doctoral studies, I have been investigating whether achieving remission based on newly proposed definitions is a pragmatic outcome in clinical trial design in order to inform the SLE researcher community on how to finetune the definitions. In another project, I am currently examining factors associated with medication non-adherence in patients with SLE residing in Sweden.
I have been conducting research within systemic lupus erythematosus together with Dr. Parodis since 2017, and since November 2020 I am a doctoral student at the KI.
During this period, we have been studying how demographical, clinical and immunological factors influence the efficacy of biological therapies in patients with SLE. We are currently exploring the impact of pharmacological and non-pharmacological factors on patients’ health-related quality of life, and the performance of different patient-reported measures as evaluation tools in clinical trials. I believe that our work highlights the importance of the patient perspective in clinical research and health care.
One of my main interests is the effective communication of results in research. I find fascination in optimising the data visualisation in the works of our research team, aiming to provide a thorough yet clear message.
I have an interest for rheumatic diseases, systemic lupus erythematosus (SLE) in particular, and I joined Dr Parodis’s research team in April 2020. I am currently involved in studies investigating health-related quality of life (HRQoL) and patient-reported outcome measures (PROMs) in SLE. PROMs are increasingly embraced in the SLE researcher community, but how they can be used in the design of clinical trials and observational studies in order to increase their ability to reflect clinically important response to therapies needs further exploration. This we attempt in several ongoing studies.
I joined Dr Parodis’s research team in October 2019 for my medical degree thesis, within the frame of which we examined the impact of body weight on adverse patient-reported health-related quality of life outcomes in patients with systemic lupus erythematosus. I have been involved in the research team ever since. My aim is to develop statistical expertise at the same time as I contribute to the projects conducted by the team, mainly projects within medical pedagogy.
I always try to look at things with a new set of eyes. Unfortunately, they don’t come with a new set of glasses.
I completed my medical education and training at the Marmara University in Istanbul as of August 2021. During my medical studies, I participated in various research projects where I developed my analytical skills on biological and clinical data at different locations, including the Karolinska Institutet and Uppsala University.
I have a particular interest in autoimmune disorders because of their complexity, ofter constituting good systems for implementing data analytics. Systemic lupus erythematosus is a very good example of such a disease with partially unclear aetiology, prominent underlying pathophysiological complexity, and variable clinical manifestations.
My main purpose is to develop computational predictive models of flare and response to therapy in patients with systemic lupus erythematosus using multilevel omics data with the aim of improving treatment outcomes and prognosis.
My interest in immunology and inflammatory diseases aligns well with the research conducted by the group, which I have found to be a warm and inspiring environment full of wonderful people. I will happily continue contributing with my efforts beyond the scope of my degree project.
Since about two years ago I have been a patient advocate in Ioannis Parodis’s research team. Having been living with SLE for many years, my involvement in research gives me the opportunity to contribute with the experience I have obtained from my own disease, combined with the information I receive from people living with rheumatic diseases whom I meet, talk with or have interviewed within the frame of my former work at the Swedish Rheumatism Association. This knowledge I also share with caregivers and researchers in lectures, conversations and book chapters.
I am a member of the editorial board of the Swedish book “Reumatologi, Studentlitteratur” (third edition as of now), and I have also have been a member of the editorial board of the book “Barnreumatologi, Studentlitteratur”. During the time I worked within the patient organisation, I composed several books, each one dealing with how to cope with a rheumatic disease. I have been reporting advances and research findings within different rheumatic diseases in special research appendices, as well as in the magazine “Bulletinen”, a magazine about rheumatic inflammatory systemic diseases by the Swedish Rheumatism Association, for which I have been the publisher and editor.
I find it important that the voice of the ones who the research is done for is heard. I find it important that people living with SLE work together with SLE researchers. Our goal is common: a better life for the people with SLE in the years to come.