Check out our new article entitled “Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus” in Journal of Autoimmunity.
Highlights
- SLE transcripts defined 3 distinct clusters: interferon, inflammation, lymphocyte signaling.
- Interferon gene upregulation denoted hematological activity and vasculitis.
- Rs7918733 T > C was associated with upregulation of CASP7 in SLE patients.
- Druggability analysis suggested CTSL activity depression through proteasome inhibition.
